Related Experiment Video
Updated: Jun 17, 2025

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Innovative Repair Method for Septal Perforation Repair: The Fascia Lata and Platelet-Rich Plasma Fusion Technique
Deniz Hanci1, Öykü İzel Onaran2, Huseyin Altun3
1Department of Otorhinolaryngology, Prof. Dr. Cemil Taşcıoğlu City Hospital, Darulaceze Cad. No: 25 Okmeydani - Sisli, Istanbul, Turkey.
This study shows that using fascia lata graft with platelet-rich plasma (PRP) effectively repairs nasal septal perforations (NSP). The innovative technique achieved a 92% closure rate in 25 patients, offering a reliable solution for NSP.
Area of Science:
- Otolaryngology
- Surgical Innovation
- Regenerative Medicine
Background:
- Nasal septal perforation (NSP) is a common complication, frequently resulting from septoplasty.
- Spontaneous healing of NSP is rare, with a tendency for progressive deterioration.
- Existing surgical repair methods for NSP vary in efficacy and complexity.
Purpose of the Study:
- To introduce and evaluate an innovative surgical technique for nasal septal perforation (NSP) repair.
- To assess the efficacy of using a fascia lata graft combined with platelet-rich plasma (PRP) for NSP restoration.
- To determine the success rate of this fusion technique across various perforation sizes.
Main Methods:
- Retrospective analysis of 25 patients undergoing NSP repair between January 2021 and January 2023.
- Open rhinoplasty technique utilized for perforation repair.
- Fascia lata graft harvested and secured in place, augmented with PRP.
Main Results:
- A 92% success rate (23 out of 25 patients) in achieving complete closure of nasal septal perforations.
- Mean follow-up period of 12 months.
- Successful closure of large perforations; smoking identified as a factor in two unsuccessful medium-sized NSP repairs.
Conclusions:
- The Fascia Lata and Platelet-Rich Plasma (PRP) fusion technique is a secure and dependable method for closing nasal septal perforations.
- This approach demonstrates a notable success rate and should be considered a viable option for NSP treatment.
- The technique shows promise for restoring nasal septal integrity, even in cases of large perforations.
More Related Videos
08:00Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
Published on: June 15, 2015
03:24Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy
Published on: January 26, 2024