Related Experiment Video
Updated: Jun 16, 2025

07:13
An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
Published on: December 7, 2016
13.2K
Anterior Segment Complications Following Intravitreal Injection
Lars H B Mackenbrock1, Gerd U Auffarth1, Michael Albrecht1
1Department of Ophthalmology, University Hospital Heidelberg, Germany.
Summary
Intravitreal injections (IVI) are common in ophthalmology but can cause anterior segment complications. While many resolve quickly, some IVI complications may increase risks during future surgeries.
Area of Science:
- Ophthalmology
- Medical Procedures
Background:
- Intravitreal injections (IVI) are increasingly prevalent, surpassing cataract surgeries in 2010.
- While posterior segment complications are well-documented, anterior segment issues are also significant.
Purpose of the Study:
- To review anterior segment complications associated with intravitreal injections.
- To highlight both immediate and potential long-term consequences of IVI.
Main Methods:
- Literature review of intravitreal injection complications.
- Analysis of reported incidence rates for various anterior segment adverse events.
Main Results:
- Common anterior segment complications include hyphema, inflammation, and implant migration.
- Specific risks include iatrogenic lens damage, accelerated cataract formation (especially with steroids), and increased surgical complications.
Conclusions:
- Intravitreal injections can lead to various immediate anterior segment complications.
- Long-term risks, particularly increased complications in subsequent surgeries, warrant further investigation.
Related Concept Videos
Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Open Angle Glaucoma: Treatment
413
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
413

