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Updated: Jun 16, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Plexiform's perplexities: a tale of two plexiform neurofibromas.
Aditya Sriharsha Pedaprolu1, Rajesh Gattani1, Suhas Jajoo1
1Department of General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra 442001, India.
Plexiform neurofibroma (PF), a rare neurofibromatosis type 1 variant, presents with characteristic skin changes. This study highlights typical and atypical cases, emphasizing surgery and follow-up for management.
Area of Science:
- Dermatology
- Oncology
- Genetics
Background:
- Plexiform neurofibroma (PF) is a rare, benign tumor arising from peripheral nerve sheaths, often associated with neurofibromatosis type 1.
- These tumors can cause significant disfigurement and involve surrounding connective and dermal tissues.
- Diagnosis is typically aided by characteristic cutaneous changes.
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