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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

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Published on: September 20, 2018

What factors influence cellular pathologists' confidence in case reporting?

Harriet Evans^1,2, Peter K Kimani³, Louise Hiller³

¹Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK. harriet.evans4@nhs.net.

Virchows Archiv : an International Journal of Pathology

|August 17, 2024

Summary

This summary is machine-generated.

Pathologist diagnostic confidence varies, influenced by case complexity and diagnostic agreement, not experience. While digital pathology shows slightly lower confidence, pathologists remain confident using it for diagnoses.

Keywords:

Breast pathology Diagnostic confidence Digital pathology Gastrointestinal pathology Renal pathology Skin pathology

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Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging

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Published on: April 8, 2016

Area of Science:

Histopathology
Digital Pathology
Medical Diagnostics

Background:

Histopathology is an interpretive discipline where pathologist diagnostic confidence varies.
Quantifying diagnostic confidence and its influencing factors in histopathology is understudied.

Purpose of the Study:

To quantify pathologist diagnostic confidence across multiple variables and specialties.
To identify factors influencing diagnostic confidence in histopathology, comparing light microscopy (LM) and digital pathology (DP).

Main Methods:

Sixteen pathologists from six NHS trusts analyzed 16,187 diagnoses across four specialties.
Each case was reported twice by each pathologist: once on LM and once on DP.
Pathologists recorded diagnostic confidence using a 7-point Likert scale for each diagnosis.

Main Results:

All investigated variables significantly predicted diagnostic confidence, except pathologist experience.
Lower confidence was associated with difficult cases, diagnostic variation (inter- and intra-pathologist), and incorrect diagnoses.
Nominally higher confidence was observed for LM (rate ratio 1.09) versus DP, though pathologists expressed confidence in DP reporting.

Conclusions:

Diagnostic confidence in histopathology is influenced by case difficulty, diagnostic agreement, and accuracy, but not experience.
External quality control and peer review are valuable for improving reporting accuracy and confidence.
While LM showed slightly higher confidence, DP is a reliable tool for histopathological diagnoses.