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Related Experiment Video

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Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats
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Chemotherapeutics in Equine Practice.

Fernando Malalana1

  • 1Philip Leverhulme Equine Hospital, University of Liverpool, Leahurst Campus, Chester High Road, Neston CH64 7TE, United Kingdom.

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Cytotoxic chemotherapy drugs treat equine skin tumors topically or intralesionally. Handle these potent drugs with extreme caution due to serious adverse effects and their carcinogenic properties.

Keywords:
ChemotherapyCytotoxicHorseTumor

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Area of Science:

  • Veterinary Medicine
  • Oncology
  • Pharmacology

Background:

  • Chemotherapy utilizes cytotoxic drugs to eliminate cancerous cells.
  • Systemic chemotherapy in horses is primarily for lymphoma.
  • Cytotoxic drugs are frequently used for accessible equine skin tumors.

Purpose of the Study:

  • To outline the use of cytotoxic drugs in equine dermatology.
  • To highlight the administration methods and safety precautions for these agents.

Main Methods:

  • Topical application of cytotoxic drug ointments.
  • Intralesional injection of cytotoxic drugs.
  • Review of safety protocols for handling cytotoxic agents.

Main Results:

  • Cytotoxic drugs are effective for treating accessible equine skin tumors.
  • Administration routes include topical and intralesional methods.
  • Significant risks of adverse effects necessitate careful handling.

Conclusions:

  • Cytotoxic drugs are valuable in equine skin tumor treatment.
  • Strict safety measures are crucial during preparation, handling, administration, and disposal.
  • The carcinogenic, mutagenic, and teratogenic potential of these drugs demands utmost caution.