Second Child After Pregnancy and Lactation-Related Osteoporosis (PLO) Treated With Teriparatide: A Case Report
Shinsuke Yamada1, Noriyuki Hayashi2, Norikazu Toi3
1Clinical Immunology, Osaka Metropolitan University of Medicine, Osaka, JPN.
Insights
Pregnancy and lactation-associated osteoporosis (PLO) is rare but serious. A patient treated with teriparatide for PLO successfully had another healthy child without recurrence, suggesting potential treatment benefits.
Area of Science:
- Reproductive medicine
- Endocrinology
- Bone metabolism
Background:
- Pregnancy and lactation-associated osteoporosis (PLO) is a rare but severe condition.
- It typically manifests during late pregnancy or early postpartum.
- Fear of recurrence often deters future pregnancies in affected individuals.
Abstract:
Pregnancy and lactation-associated osteoporosis (PLO) is one of the rarest and most serious primary osteoporotic conditions that develops during the third trimester of gestation and/or early postpartum period. A history of PLO often causes individuals to hesitate when considering an additional child due to anxiety about recurrence risk. Reported here are details of a 29-year-old patient with PLO given aggressive treatment for osteoporosis with teriparatide who subsequently gave birth to a healthy child at age 33 without PLO recurrence. Further case studies are needed to examine the efficacy and safety of PLO treatment and to provide beneficial results for those who wish to have another pregnancy.
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