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NanoLuciferase technology-based detection of TMPRSS2 as attempt to develop anti-coronavirus agents
Yanwen Chen1, Yunqi Li2, Ye Zhao1
1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Rd, Shanghai, 200025, China.
Biochemistry and Biophysics Reports
|August 19, 2024
Abstract:
•Utilized NanoBiT technology for high-throughput screening.•Identified compounds reducing TMPRSS2 expression, a crucial step for SARS-CoV-2 entry.•Explored a broad range of compound libraries.
