Intra- and interobserver reliability of ocular surface analyzer LacryDiag®
Eva Kos1,2, Valentina Cigić1,2, Mladen Bušić1,2
1University Eye Clinic, University Hospital "Sveti Duh", Sveti Duh 64, Zagreb 10000, Croatia.
International Journal of Ophthalmology
|August 19, 2024
Summary
The LacryDiag ocular surface analyzer demonstrated excellent reliability for evaluating tear meniscus height (TMH) and meibography (MBG). However, interferometry showed poor interobserver reliability, indicating a need for improvement in this specific measurement.
Area of Science:
- Ophthalmology
- Optometry
- Biomedical Engineering
Background:
- Dry eye disease diagnosis relies on objective measurements of the ocular surface.
- The LacryDiag ocular surface analyzer offers multiple assessment tools, including interferometry, tear meniscus height (TMH), and meibography (MBG).
- Understanding the reliability of these measurements is crucial for clinical application.
Purpose of the Study:
- To investigate the intra- and interobserver reliability of the LacryDiag ocular surface analyzer.
- Specifically assess the reliability of interferometry, TMH measurement, and MBG using the LacryDiag device.
Main Methods:
- Two examiners performed five consecutive measurements of interferometry, TMH, and MBG using the LacryDiag.
- Intra- and interobserver reliability were assessed using Cohen's kappa for interferometry and intraclass correlation coefficient for TMH and MBG.
Main Results:
- Excellent intraobserver reliability was found for MBG (0.955-0.970).
- Intraobserver reliability for TMH was excellent for one observer (0.863) and fair-to-good for the other (0.431).
- Interferometry showed poor interobserver reliability (0.074) and variable intraobserver reliability (0.799 and 0.535).
Conclusions:
- The LacryDiag is a reliable noninvasive tool for evaluating TMH and MBG.
- Interferometry measurements require further refinement due to poor interobserver and variable intraobserver reliability.
