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Updated: Jun 16, 2025

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
Oral squamous cell carcinoma: A 26 years institutional cross-sectional study
Dipak D Ghatage1, Ashwini G Kendre1, Devendra H Palve1
1Department Oral Pathology and Microbiology, GDCH, Nagpur, Maharashtra, India.
Context:
The variance in the prevalence of oral squamous cell carcinoma (OSCC) around the world has been associated with a number of sociocultural traits, significant regional variations in risk factors, variations in data gathering, and the degree of health service development in different populations. Here, we undertake a 26 years institutional review and analysis of OSCC cases.
Aim:
To evaluate and analyse 26 years Institutional Data of OSCC.
Settings And Design:
Department of Oral and Maxillofacial Pathology's archives, Government Dental College and Hospital, Nagpur, Maharashtra, and observational cross-sectional study.
Methods And Material:
This study examines instances of OSCC that were histologically diagnosed between 1997 and 2022. All information pertaining to cases of OSCC was obtained from the departmental archives.
Statistical Analysis Used:
Data tabulated and then subjected to descriptive statistical analysis with the SPSS statistical software.
Results:
The total number of the patients included 1508 (69.6%) males and 660 (30.4%) females, whose age ranged from the second decade to the tenth decade of life with a mean age of 55.5 years with a range of 20-91 years. The incidence was the highest in the fifth and sixth decades (n = 603, 27.8% and n = 572, 26.4%), respectively. The left buccal mucosa recorded the maximum number of cases (left buccal mucosa 559, 25.8%). There were 1405 (64.8%) cases of well-differentiated SCC, 301 (13.9%) cases of moderately differentiated SCC, and 51 (2.4%) cases of poorly differentiated SCC.
Conclusions:
The overall incidence and prevalence of OSCC can be estimated using baseline epidemiological data from our institution.
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