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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Related Experiment Video

Updated: Jun 16, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

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[Perineal prostate biopsy].

Paulo Leonardo Pfitzinger1, Darjusch Andreas Askari2, Troya Ivanova2

  • 1Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Marchioninistr. 15, 81377, München, Deutschland. paulo.pfitzinger@med.uni-muenchen.de.

Urologie (Heidelberg, Germany)
|August 19, 2024
PubMed
Summary
This summary is machine-generated.

Transperineal biopsy (TP-Bx) offers improved prostate cancer detection and lower infection rates compared to transrectal biopsy (TR-Bx). Studies show TP-Bx can be safely performed without antibiotics, with advanced techniques yielding precise results.

Keywords:
Antibiotic prophylaxisBiopsy methodLocal anesthesiaProstatic neoplasmsTissue sample

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Area of Science:

  • Urology
  • Oncology
  • Surgical Techniques

Background:

  • Prostate cancer diagnosis relies heavily on prostate biopsy.
  • Transrectal biopsy (TR-Bx) is the current standard in Germany.
  • Transperineal biopsy (TP-Bx) is gaining traction due to improved outcomes.

Purpose of the Study:

  • To review the evolution of perineal biopsy techniques.
  • To compare transrectal biopsy (TR-Bx) and transperineal biopsy (TP-Bx).
  • To evaluate the necessity of antibiotic prophylaxis for TP-Bx.

Main Methods:

  • Comparative analysis of TR-Bx and TP-Bx.
  • Review of current literature on biopsy techniques and outcomes.
  • Discussion of antibiotic prophylaxis guidelines.

Main Results:

  • TP-Bx demonstrates lower infection rates and higher cancer detection rates than TR-Bx.
  • Evidence suggests TP-Bx can be performed effectively without antibiotic prophylaxis.
  • Novel methods like robotic-assisted and vector biopsy offer high precision.

Conclusions:

  • TP-Bx is an increasingly recommended method for prostate cancer diagnosis.
  • Technological advancements and funding support the adoption of TP-Bx.
  • The choice of biopsy method should be a shared decision between clinician and patient.