Related Experiment Video
Updated: Aug 17, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Function of vitamin A in the respiratory tract
Insights
Vitamin A (retinol) is essential for the healthy development of lung tissue in infants. Ensuring adequate vitamin A levels may improve nutritional care for premature babies.
Area of Science:
- Pulmonology
- Nutritional Science
- Developmental Biology
Background:
- Vitamin A (retinol) plays a crucial role in epithelial cell differentiation.
- Tracheal and bronchopulmonary epithelium development is vital for lung function.
Purpose of the Study:
- To review the evidence supporting vitamin A's role in lung epithelial differentiation.
- To explore the implications of vitamin A status in premature infants for nutritional management.
Main Methods:
- Literature review of existing studies on vitamin A and lung development.
- Analysis of recent research on vitamin A status in premature infants.
Main Results:
- Strong evidence indicates vitamin A is necessary for initiating and maintaining proper differentiation of the respiratory epithelium.
- Vitamin A deficiency can impair lung tissue development.
Conclusions:
- Vitamin A is a critical nutrient for normal development of the trachea and lungs.
- Assessing and managing vitamin A status in premature infants is important for optimizing their nutritional care and respiratory health.
Abstract:
Solid old and more recent evidence reviewed here suggests strongly that vitamin A (retinol) functions as a necessary factor for the initiation and maintenance of proper differentiation of tracheal and bronchopulmonary epithelium. Recent examinations of the vitamin A status of children born prematurely may help to design an improved nutritional management of these patients.
Related Concept Videos
The Respiratory System
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Anatomy of Respiratory System I: Upper Respiratory Tract
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Microbiota of the Respiratory Tract
Respiratory Syncytial Virus Disease

