Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Testes: Histology01:27

Testes: Histology

771
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
771
Testes: Gross Anatomy01:19

Testes: Gross Anatomy

1.8K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
1.8K
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

367
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
367
Spermatogenesis01:41

Spermatogenesis

102.3K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.3K
Infertility in Males01:23

Infertility in Males

256
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
256
Sperm Transport01:15

Sperm Transport

717
The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
717

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Multidisciplinary Approach to Addressing Barriers in Osteoporosis Screening, Diagnosis, Therapy Sequencing, and Adherence in India.

Cureus·2026
Same author

The Carbothalamus: Villain and Victim in Metabolic Care.

JPMA. The Journal of the Pakistan Medical Association·2026
Same author

Inhaled Insulin: Place in Therapy.

JPMA. The Journal of the Pakistan Medical Association·2026
Same author

Meta-Pharmacologic Support and Scaffolding for Obesity Therapy.

JPMA. The Journal of the Pakistan Medical Association·2026
Same author

Novel Clinical and Pre-clinical Obesity Estimates in Older Indian Adults: Insights from a Nationally Representative Dataset.

Diabetes therapy : research, treatment and education of diabetes and related disorders·2026
Same author

Global trends in the prevalence of type 2 diabetes mellitus: understanding trajectories through conceptual frameworks.

Hormones (Athens, Greece)·2026
Same journal

Predictors of Altmetric Score in Top-Cited Orthopaedic Articles: A Bibliometric Analysis.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Carbon footprint of waste generated in orthopaedic cases in Pakistan: a pilot descriptive study.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Enhancing quotation accuracy assessment with Chatpdf - a game-changer for a century-old conundrum.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Barriers to implementing simulation-based surgical training for improving quality and safety in developing countries: A short communication.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Intraoperative Adverse Event Reporting in Gastrointestinal Cancer Surgery: A Narrative Review on the Application of ClassIntra.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

The Impact of Mortality and Morbidity Meetings on Quality Improvement and Patient Safety.

JPMA. The Journal of the Pakistan Medical Association·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2025

Teratoma Generation in the Testis Capsule
05:24

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

20.8K

Testomalacia.

Sanjay Kalra1, Atul Dhingra2, Nitin Kapoor3

  • 1Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India.

JPMA. the Journal of the Pakistan Medical Association
|August 20, 2024
PubMed
Summary
This summary is machine-generated.

We propose the new diagnostic term "testomalacia" to describe testicular softness or conditions related to testosterone dysfunction. This single term effectively captures various causes of functional androgen deficiency across all ages.

Keywords:
Hypogonadism, Late Onset Hypogonadism (LOH), Male Health, Testes, Testosterone, Testosterone Deficiency

More Related Videos

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
10:41

Germ Cell Transplantation and Testis Tissue Xenografting in Mice

Published on: February 6, 2012

29.7K
Author Spotlight: A Simple and Cost-Effective Method for Leukocyte Analysis in Semen
04:36

Author Spotlight: A Simple and Cost-Effective Method for Leukocyte Analysis in Semen

Published on: January 19, 2024

4.0K

Related Experiment Videos

Last Updated: Jun 16, 2025

Teratoma Generation in the Testis Capsule
05:24

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

20.8K
Germ Cell Transplantation and Testis Tissue Xenografting in Mice
10:41

Germ Cell Transplantation and Testis Tissue Xenografting in Mice

Published on: February 6, 2012

29.7K
Author Spotlight: A Simple and Cost-Effective Method for Leukocyte Analysis in Semen
04:36

Author Spotlight: A Simple and Cost-Effective Method for Leukocyte Analysis in Semen

Published on: January 19, 2024

4.0K

Area of Science:

  • Andrology
  • Endocrinology
  • Urology

Background:

  • Current terminology for testicular dysfunction is fragmented.
  • Existing terms may not encompass all aspects of androgen deficiency.
  • A unified term is needed for clarity and broader application.

Purpose of the Study:

  • To introduce and define the term 'testomalacia'.
  • To propose 'testomalacia' as a comprehensive diagnostic descriptor for testicular conditions and functional androgen deficiency.
  • To highlight the advantages of 'testomalacia' over existing terminology.

Main Methods:

  • Conceptual introduction of a new diagnostic term.
  • Definition and etymological exploration of 'testomalacia'.
  • Comparative analysis with existing terms for testicular and androgen-related conditions.

Main Results:

  • 'Testomalacia' is proposed to describe testicular softness (anatomic/functional) or illness related to testosterone secretion/function.
  • 'Testomalacia' offers a single, encompassing term for functional androgen deficiency.
  • The term is applicable across all age groups and various etiologies.

Conclusions:

  • 'Testomalacia' provides a concise and descriptive diagnostic term.
  • It unifies the description of diverse conditions related to testicular function and testosterone.
  • Adoption of 'testomalacia' could enhance clinical communication and understanding of androgen deficiency.