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Changes in analgesic prescriptions in Dutch general practice.

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Strong opioid prescriptions increased in Dutch general practice, particularly for non-malignant pain. Risk factors for chronic opioid use include older age, lower education, and certain health conditions.

Keywords:
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Area of Science:

  • General Practice
  • Pharmacology
  • Public Health

Background:

  • Opioid prescription trends in Dutch general practice are not well understood.
  • Recent changes in analgesic prescribing patterns require investigation.

Purpose of the Study:

  • To analyze trends in analgesic prescriptions (paracetamol, NSAIDs, opioids) in Dutch general practice.
  • To examine indications for strong opioid prescribing.
  • To identify risk factors for chronic opioid use.

Main Methods:

  • Retrospective cohort study (2013-2022) using a primary care research network.
  • Included patients with at least one analgesic prescription.
  • Analyzed prescription numbers, indications, and risk factors for chronic use.

Main Results:

  • Strong opioid prescriptions increased, while paracetamol, NSAIDs, and weak opioid prescriptions decreased.
  • Strong opioids were increasingly prescribed for non-malignant pain.
  • Risk factors for chronic opioid use included older age, lower education, smoking, and history of specific disorders or abuse.

Conclusions:

  • General practitioners must be vigilant about increased strong opioid prescribing for benign conditions.
  • Monitoring psychosocial factors is crucial for preventing harms from chronic opioid use.