Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Histamine and the gut.

B I Hirschowitz

    New England and Regional Allergy Proceedings
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Histamine plays a key role in regulating gastric acid secretion. Histamine H2 antagonists are effective treatments for various gastrointestinal disorders, including duodenal ulcers.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Vitamin B12 deficiency in hypersecretors during long-term acid suppression with proton pump inhibitors.

    Alimentary pharmacology & therapeutics·2008
    Same author

    Chromogranin A in patients with acid hypersecretion and/or hypergastrinaemia.

    Alimentary pharmacology & therapeutics·2007
    Same author

    Usual and unusual causes of duodenal ulcer.

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2003
    Same author

    Minor effects of Helicobacter pylori on gastric secretion and dose of lansoprazole during long-term treatment in ZE and non-ZE acid hypersecretors.

    Alimentary pharmacology & therapeutics·2002
    Same author

    Long-term lansoprazole control of gastric acid and pepsin secretion in ZE and non-ZE hypersecretors: a prospective 10-year study.

    Alimentary pharmacology & therapeutics·2001
    Same author

    Pernicious anemia and stomach cancer.

    Scandinavian journal of gastroenterology·2001
    Same journal

    Official abstracts of papers o the XIII International Congress of Allergology and Clinical Immunology (ICACI). October 16-21, 1988, Montreux, Switzerland.

    New England and regional allergy proceedings·1988
    Same journal

    A new look at conifer allergy.

    New England and regional allergy proceedings·1988
    Same journal

    Eastern pine sensitivity in New England.

    New England and regional allergy proceedings·1988
    Same journal

    Mountain cedar pollinosis: can it occur in non-atopics?

    New England and regional allergy proceedings·1988
    Same journal

    The management of patients with sulfonamide allergy.

    New England and regional allergy proceedings·1988
    Same journal

    Exercise-induced anaphylaxis.

    New England and regional allergy proceedings·1988
    See all related articles

    Area of Science:

    • Gastroenterology
    • Pharmacology

    Background:

    • Histamine is a crucial mediator in the gastrointestinal system.
    • Its role influences gastric acid, pepsin, and intrinsic factor secretion.
    • Histamine's effects vary across different species.

    Purpose of the Study:

    • To review the multifaceted role of histamine in gut physiology.
    • To explore histamine's impact on gastrointestinal circulation and musculature.
    • To critically evaluate the therapeutic applications of histamine antagonists.

    Main Methods:

    • Review of existing literature on histamine's gastrointestinal functions.
    • Analysis of interactions between histamine and other signaling molecules.
    • Examination of preclinical and clinical data on histamine antagonist efficacy.

    Related Experiment Videos

    Main Results:

    • Histamine modulates gastric secretion, with species-specific differences.
    • Histamine H1 and H2 receptors affect gastrointestinal motility and blood flow.
    • Histamine H2 antagonists demonstrate significant therapeutic benefits.

    Conclusions:

    • Histamine is integral to gastric secretion control.
    • Histamine H2 antagonists are vital in managing acid-related gastrointestinal diseases.
    • Further research can refine therapeutic strategies involving histamine modulation.