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Long-term application of wearable artificial endocrine pancreas--closed-loop intravenous vs subcutaneous insulin
M Shichiri1, R Kawamori, Y Goriya
1First Department of Medicine, Osaka University Medical School, Japan.
Life Support Systems : the Journal of the European Society for Artificial Organs
|January 1, 1985
Abstract:
For closed-loop glycemic control on IDDM, closed-loop sc insulin infusion algorithm has developed by analysing the pharmacokinetics of sc insulin absorption. With the algorithm, daily glycemic excursion in IDDMs was controlled to near-normal levels. These data suggested that the closed-loop sc insulin infusion algorithm might be feasible to regulate glycemia in diabetic patients for a long-term period by wearable artificial endocrine pancreas.