[Reversibility of a critical intraventricular conduction delay under flecainide and lacosamide by sodium bicarbonate]
Anja Gallinger1, Rahman Osei-Davies2, F Hennersdorf3
1Klinik für Innere Medizin, Kardiologie und Angiologie, Schön Klinik Eilbek, Dehnhaide 120, 22081, Hamburg, Deutschland. agallinger@schoen-klinik.de.
Abstract:
The case of a 72-year-old female patient with arrhythmogenic syncope associated with a combination therapy of flecainide and lacosamide is presented. The authors believe in an additive effect of both drugs on myocardial voltage-gated sodium channels with extraordinary QRS widening, exit block with temporary pacing and complete reversibility through infusion of sodium bicarbonate as bail-out therapy.
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