Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

Barrett Esophagus-I: Introduction

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...

Cancer Cell Migration through Invadopodia

Cancer Cell Migration through Invadopodia

Invadosome is a broad category of cell surface structures with proteolytic activity that degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Honokiol and Its Emerging Role in Breast Cancer Therapy.

Cancers·2026

Same author

Plasma Regulates Homeostatic Pulmonary Endothelial Signaling to Mitigate Vascular Leak Following Polytrauma and Hemorrhagic Shock.

Shock (Augusta, Ga.)·2026

Same author

Oropharyngeal Cartilaginous Choristoma Presenting as a Unilateral Mass.

Head and neck pathology·2026

Same author

Plasma regulates homeostatic pulmonary endothelial signaling to mitigate vascular leak following polytrauma and hemorrhagic shock.

bioRxiv : the preprint server for biology·2026

Same author

Mucoacinar Carcinoma of the Parotid Gland.

Head and neck pathology·2026

Same author

Targeted RNA sequencing of thyroid tumors from individuals with PTEN hamartoma tumor syndrome reveals a unique transcriptome with a predominantly RAS-like expression profile.

Surgery·2025

Search research articles

Related Experiment Video

Updated: Jun 15, 2025

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Published on: January 3, 2013

Palisading Adenocarcinoma.

Melad N Dababneh¹, Christopher C Griffith^1,2, Kaitlyn Ooms³

¹Pathology and Laboratory Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue L15, Cleveland, OH, 44195, USA.

Head and Neck Pathology

|August 21, 2024

Summary

Palisading adenocarcinoma, a rare salivary gland tumor, primarily affects the sublingual gland. This study details its characteristics to enhance understanding of this distinct neoplasm.

Keywords:

Palisading adenocarcinoma Sublingual gland

More Related Videos

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Published on: February 2, 2024

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Related Experiment Videos

Last Updated: Jun 15, 2025

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Immunohistochemical Staining of B7-H1 PD-L1 on Paraffin-embedded Slides of Pancreatic Adenocarcinoma Tissue

Published on: January 3, 2013

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Published on: February 2, 2024

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Area of Science:

Pathology
Oncology
Head and Neck Surgery

Background:

Palisading adenocarcinoma is a recently identified salivary gland neoplasm.
This tumor shows a predilection for the sublingual gland.
Limited literature exists on its specific characteristics.

Purpose of the Study:

To describe the experience with palisading adenocarcinoma.
To corroborate and expand existing literature on this neoplasm.
To further clarify the phenotype of palisading adenocarcinoma.

Main Methods:

Retrospective case review.
Histopathological analysis.
Immunohistochemical staining (if applicable).

Main Results:

Detailed description of morphological features.
Clinical and pathological data presentation.
Comparison with similar entities.

Conclusions:

Palisading adenocarcinoma is a distinct entity within salivary gland tumors.
Further characterization aids in diagnosis and management.
Sublingual gland is a key site for this neoplasm.