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Updated: Jun 15, 2025

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Percutaneous Sclerotherapy of Venous Malformations
1Boston Children's Hospital, Harvard Medical School, Department of Radiology, Division of Pediatric Interventional Radiology, University of North Carolina at Chapel Hill, School of Medicine, Boston, MA; Department of Radiology, Division of Vascular and Interventional Radiology, University of North Carolina Medical Center, Boston, MA.
Abstract:
Venous malformation (VM) stands as the most prevalent form of vascular malformation, characterized by its diverse morphology. These lesions can manifest in any part of the body, affecting different tissue planes and giving rise to symptoms such as pain, swelling, or physical dysfunction. In the realm of treatment, direct puncture VM sclerotherapy holds its place as the primary approach. This technique involves the administration of a sclerosing agent into the VM channels during contrast phlebography while simultaneously managing the outflow veins through different methods. The process of VM sclerotherapy induces endothelial damage, thrombosis, and fibrosis, resulting in symptom relief through lesion shrinkage. It is crucial to exercise caution techniques and sclerosing agents during VM sclerotherapy to minimize procedural complications, enhance clinical outcomes, and ultimately improve the patient's overall quality of life.
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