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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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Marijuana's Impact On Implant-based Breast Reconstruction: A Retrospective Cohort Study
Tala Al-Saghir1, Jamie Hall2, Michael Diffley3
1From the Division of Otolaryngology, Henry Ford Health System, Detroit, Mich.
Plastic and Reconstructive Surgery. Global Open
|August 22, 2024
Summary
Active marijuana use significantly increases complication risks, including infection and reoperation, in patients undergoing immediate direct-to-implant breast reconstruction. Abstinence from cannabis is advised before surgery to improve outcomes.
Area of Science:
- Plastic Surgery
- Oncology
- Surgical Outcomes
Background:
- Chronic marijuana use is linked to vascular and cardiac issues.
- The impact of cannabis on wound healing in breast reconstruction is not well-understood.
- Increasing marijuana use necessitates understanding its surgical implications.
Purpose of the Study:
- To investigate the association between active cannabis use and complications in immediate direct-to-implant (DTI) breast reconstruction.
- To identify specific surgical outcomes affected by perioperative marijuana consumption.
Main Methods:
- Retrospective cohort study of 243 patients undergoing immediate DTI breast reconstruction.
- Active cannabis use defined as use within 12 weeks of surgery.
- Chart review for patient demographics, operative details, and surgical complications; statistical analyses performed.
Main Results:
- 12 patients (4.9%) reported active cannabis use.
- Active marijuana users had higher rates of cellulitis, explantation for infection, ED visits, readmission, and reoperation within 90 days.
- Multivariable analysis showed active cannabis use increased odds of cellulitis (OR=3.55), reoperation (OR=4.75), and major complications (OR=2.26).
Conclusions:
- Perioperative cannabis consumption is associated with increased complication rates in immediate DTI breast reconstruction.
- Further research with larger cohorts is needed to confirm these findings.
- Abstinence from cannabis use in the perioperative period should be strongly considered.
