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Published on: September 19, 2014
Thiophene assisted cellular uptake enhancement for highly efficient NIR-II cancer phototheranostics
Yue Zhang1, Jia Yu1, Chunbin Li1
1College of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, P. R. China. jiangguoyu@mail.ipc.ac.cn.
Abstract:
We designed two series of NIR-II PTAs with D-A or D-A-D structures, in which the introduction of thiophene promotes a bathochromic shift of emission into the NIR-II region, helps to improve the cellular uptake of the PTAs and facilitates NIR-II imaging-guided PDT/PTT cancer phototherapy.
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