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Pseudomonas aeruginosa in chronic maxillary sinusitis
Abstract:
Pseudomonas aeruginosa (Ps. Au.) infection of the maxillary sinus has been reported as an incidental finding on routine antrostomy; however, it has also been noted in several studies as the significant organism in the etiology of chronic sinusitis. Four case reports of culture verified Ps. Au. maxillary sinusitis are presented. The therapeutic modality used in two of the cases was a Caldwell-Luc operation and in two, an intranasal antrostomy. In all cases, multiple irrigations through the surgically created nasoantral windows were done postoperatively, as was the instillation of gentamicin ophthalmic drops intranasally. In all four cases the infection cleared with this combined surgical and medical therapy.
Insights
Pseudomonas aeruginosa (Ps. Au.) maxillary sinusitis, often incidental, can cause chronic sinusitis. Combined surgical and medical therapy, including gentamicin drops, effectively cleared infection in four reported cases.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Microbiology
Background:
- Pseudomonas aeruginosa (Ps. Au.) is an opportunistic pathogen.
- Ps. Au. maxillary sinusitis can be an incidental finding or a significant etiological factor in chronic sinusitis.
Observation:
- Four cases of culture-verified Ps. Au. maxillary sinusitis were analyzed.
- Therapeutic approaches included Caldwell-Luc operation and intranasal antrostomy.
- Postoperative management involved multiple irrigations and intranasal gentamicin ophthalmic drops.
Findings:
- Combined surgical and medical management led to successful clearance of infection in all four cases.
- Intranasal gentamicin instillation demonstrated efficacy in treating Ps. Au. maxillary sinusitis.
Implications:
- This study highlights effective treatment strategies for Ps. Au. maxillary sinusitis.
- The findings support a combined surgical and medical approach for refractory cases.
- Further research into targeted antibiotic delivery for sinusitis may be warranted.