Related Experiment Video
Updated: May 1, 2026

3D Imaging of PDL Collagen Fibers during Orthodontic Tooth Movement in Mandibular Murine Model
Published on: April 15, 2021
[Research progress on labial protuberances of anterior teeth in orthodontic treatment]
Dingwen Luo1, Sijie Wang2, Lu Gao2
1The Stomatology Hospital, Zhejiang University School of Medicine, Zhejiang University School of Stomatology, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang Provincial Key Laboratory of Oral Biomedical Research, Zhejiang University Cancer Center, Zhejiang Provincial Engineering Research Center of Oral Biomaterials and Devices, Hangzhou 310006, China. 22118719@zju.edu.cn.
Abstract:
During orthodontic treatment, irregular and varying sized nodular bony protrusions may sometimes appear on the labial side of the patient's anterior alveolar bone, which is closely related to the differential bone remodeling on the inner and outer surfaces of the alveolar bone. Labial protuberances not only affect the aesthetic results of orthodontic treatment, but also pose potential risks to periodontal health. Currently, it is believed that the influencing factors of the formation of the labial protuberances may be related to the patient's gender and age, tooth movement speed, and extent of anterior teeth retraction. Labial protuberances typically resolve spontaneously, however, if persistent, alveoloplasty may be necessary for treatment. This review provides a summary on the occurrence, influencing factors of formation, potential biological mechanisms, and corresponding treatment methods of labial protuberances during orthodontic treatment.

