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Unusual presentation in a case of diffuse large B-cell lymphoma
Priya Das1, Kaustubh Gupta1, Gaurav Raj1
1Department of Radio-diagnosis, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Radiology Case Reports
|August 26, 2024
Summary
Diffuse large B-cell lymphoma can unusually present as a ureteric obstruction. This case highlights lymphoma mimicking a urinary tract infection, emphasizing the need for broader diagnostic considerations.
Area of Science:
- Oncology
- Urology
- Pathology
Background:
- Non-Hodgkin's lymphoma (NHL) comprises diverse lymphoid neoplasms, often affecting extranodal sites.
- Ureteric involvement in NHL is rare, with diffuse large B-cell lymphoma (DLBCL) presenting uniquely.
Observation:
- A patient presented with symptoms mimicking a urinary tract infection, including pyelonephritis and ureteritis.
- Initial presentation was unresponsive to antibiotics, with no positive urine culture, suggesting an atypical infection.
Findings:
- Radiological imaging showed significant soft tissue thickening of the ureter, extending from the renal pelvis.
- Fine-needle aspiration cytology (FNAC) and biopsy confirmed lymphomatous involvement of the ureter.
Implications:
- This case underscores the importance of considering lymphoma in the differential diagnosis of unexplained ureteric obstruction and UTI-like symptoms.
- Highlights the varied clinical presentations of secondary ureteric involvement by lymphoma.
- Emphasizes the need for thorough investigation beyond standard infection protocols for refractory urinary symptoms.
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