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Related Experiment Video

Updated: Jun 15, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

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Comparison of Eye Axial Length Measurements Taken Using Partial Coherence Interferometry and OCT Biometry.

Nicola Rizzieri1,2, Alessio Facchin3,4

  • 1Optometry and Vision Science, University of Latvia, LV-1586 Riga, Latvia.

Vision (Basel, Switzerland)
|August 27, 2024
PubMed
Summary

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Optometry and vision science : official publication of the American Academy of Optometry·2024

Partial coherence interferometry (PCI) and spectral domain optical coherence tomography (SD-OCT) accurately measure axial length for myopia management. While interchangeable for single measurements, caution is advised for longitudinal comparisons.

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Medical Devices

Background:

  • Accurate axial length measurement is crucial for myopia management.
  • Comparing different optical biometry devices is essential for clinical practice.
  • Partial coherence interferometry (PCI) and spectral domain optical coherence tomography (SD-OCT) are common biometry techniques.

Purpose of the Study:

  • To evaluate the inter-device measurement agreement between PCI and SD-OCT for axial length.
  • To assess the suitability of these devices for myopia management applications.
  • To determine interchangeability for clinical use and longitudinal studies.

Main Methods:

  • Bland-Altman analysis was used to assess agreement between PCI and SD-OCT measurements.
  • Linear mixed models were employed for statistical comparison of measurements.
Keywords:
OCTaxial lengthbiometrymyopiapartial coherence interferometry

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  • Axial length was measured in 82 eyes from 41 adult participants.

    • Main Results:

    • A near-zero and non-significant bias was found between PCI and SD-OCT measurements.
    • The 95% limits of agreement were determined to be 0.06 mm.
    • Both devices demonstrated high accuracy in axial length measurement.

    Conclusions:

    • PCI and SD-OCT exhibit excellent agreement for single axial length measurements.
    • These devices are interchangeable for cross-sectional assessments in myopia management.
    • Longitudinal comparisons require careful consideration due to potential subtle differences.