Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.0K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial.

Circulation. Heart failure·2025
Same author

Impact of Rurality and Geographical Accessibility on Stroke Care and Outcomes.

Stroke·2025
Same author

Field-cycling imaging yields repeatable brain R<sub>1</sub> dispersion measurement at fields strengths below 0.2 Tesla with optimal fitting routine.

Magma (New York, N.Y.)·2025
Same author

Field cycling imaging to characterise breast cancer at low and ultra-low magnetic fields below 0.2 T.

Communications medicine·2024
Same author

Trial of the cerebral perfusion response to sodium nitrite infusion in patients with acute subarachnoid haemorrhage using arterial spin labelling MRI.

Nitric oxide : biology and chemistry·2024
Same author

Improved quantification in CEST-MRI by joint spatial total generalized variation.

Magnetic resonance in medicine·2024

Related Experiment Video

Updated: Jun 15, 2025

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
08:39

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

13.4K

Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T.

Vasiliki Mallikourti1, P James Ross1, Oliver Maier1

  • 1From the Aberdeen Biomedical Imaging Centre (V.M., P.J.R., E.F., D.J.L., L.M.B.) and Institute of Medical Sciences (M.J.M.), University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, United Kingdom; Institute of Medical Engineering, Graz University of Technology, Graz, Austria (O.M.); and Acute Stroke Unit, Aberdeen Royal Infirmary, Aberdeen, United Kingdom (G.G.G.).

Radiology
|August 27, 2024
PubMed
Summary
This summary is machine-generated.

Field-cycling imaging (FCI) can identify subacute ischemic stroke by detecting T1 relaxation changes at low magnetic fields. This new imaging technique shows promise for stroke diagnosis, offering novel contrast mechanisms.

More Related Videos

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
05:23

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders

Published on: May 31, 2024

513
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

14.1K

Related Experiment Videos

Last Updated: Jun 15, 2025

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
08:39

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

13.4K
Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
05:23

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders

Published on: May 31, 2024

513
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

14.1K

Area of Science:

  • Medical Imaging
  • Biophysics
  • Neurology

Background:

  • Field-cycling imaging (FCI) measures T1 relaxation time constants across a range of low magnetic fields (0.2-200 mT).
  • FCI offers novel contrast mechanisms potentially useful for stroke detection, beyond conventional MRI capabilities.
  • This technology was developed at the University of Aberdeen.

Purpose of the Study:

  • To evaluate a prototype whole-body FCI scanner for identifying infarct regions in subacute ischemic stroke patients.
  • To assess the feasibility of using FCI as an alternative imaging modality for stroke.

Main Methods:

  • Prospective study of adult patients with confirmed ischemic stroke admitted to a stroke unit.
  • FCI scans acquired 1-6 days post-ictus at 0.2 mT to 0.2 T with varying evolution times.
  • T1 maps generated; infarct regions compared to contralateral unaffected brain using Wilcoxon signed-rank test.

Main Results:

  • FCI scans below 0.2 T showed hyperintense T1 regions corresponding to infarcts, with 86% interrater agreement.
  • Infarct-to-contralateral tissue contrast increased as magnetic field strength decreased (r = -0.68, P < .001).
  • T1 dispersion slopes differed significantly between infarct and unaffected tissues (P = .03).

Conclusions:

  • Whole-brain FCI effectively identifies subacute ischemic stroke using T1 relaxation mechanisms.
  • FCI can detect stroke at magnetic field strengths as low as 0.2 mT.
  • This technique demonstrates potential as a valuable tool in stroke imaging.