Rh(III)-Catalyzed [3 + 3]-Coupling Cyclization of 3-Hydroxyisoindolinones with Carbenoids: Rapid Access to
Chengjie Wang1, Huanfeng Jiang1, Wei Zeng1
1Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China.
Abstract:
A Rh(III)-catalyzed [3 + 3]-coupling cyclization of 3-hydroxy-3-phenylisoindolinone with carbenoids has been developed. The method provides an efficient approach to access polyfunctionalized-spiro[isochromene-1,1'-isoindolin]-3'-ones with good to excellent reaction conversions.
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