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Updated: Jun 15, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
[Research progress on eosinophil heterogeneity in asthma]
Yan Chen1,2,3, Song-Min Ying4,2, Chao Zhang5,2
1Institute of Respiratory Diseases, Zhejiang University, Hangzhou 310030, China.
Abstract:
Asthma is a heterogeneous disease characterized by chronic airway inflammation. More than half of asthma cases are induced by allergens. Eosinophils accumulate in large numbers in the airways, and their number is closely related to the severity of asthma. In recent years, extensive research has been conducted on the pathogenesis of eosinophils in asthma and the targeted therapeutic drugs for them. This article mainly reviews the research progress on the important role of eosinophil heterogeneity in the occurrence and development of asthma, and provides ideas for the personalized and precise treatment of asthma in the future.
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