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Published on: May 16, 2019
Zinc and Diabetes: A Connection between Micronutrient and Metabolism
Rahnuma Ahmad1, Ronald Shaju2, Azeddine Atfi3
1Department of Physiology, Medical College for Women and Hospital, Dhaka 1230, Bangladesh.
Zinc, an essential micronutrient, plays a vital role in regulating blood glucose and insulin. Studies suggest adequate zinc levels may help prevent diabetes complications and improve management in diabetic patients.
Area of Science:
- Endocrinology
- Nutritional Science
- Metabolic Disorders
Background:
- Diabetes mellitus is a significant global health issue with high mortality and morbidity.
- Current management focuses on oral medications, insulin, and macronutrient-focused diets.
- Micronutrient deficiencies, particularly zinc, are linked to insulin resistance and glucose intolerance.
Purpose of the Study:
- To review the role of zinc in glucose metabolism.
- To examine the impact of zinc inadequacy on diabetes development and complications.
- To assess the potential benefits of zinc supplementation in diabetes prevention and management.
Main Methods:
- Literature review of human studies and scientific evidence.
- Analysis of zinc's biochemical functions related to insulin.
- Synthesis of data on zinc's effects on glucose regulation and diabetes.
Main Results:
- Zinc acts as a chemical messenger and cofactor, crucial for insulin synthesis, release, and storage.
- Zinc deficiency is associated with increased insulin resistance and glucose intolerance.
- Adequate zinc levels may reduce the risk of diabetic complications.
Conclusions:
- Zinc is an important trace element for blood glucose regulation.
- Zinc supplementation shows potential benefits for managing diabetes.
- Further large-scale clinical trials are needed to confirm zinc's utility in diabetes care.
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