Related Experiment Video
Updated: Jun 15, 2025

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Potential mechanisms of ischemic stroke induced by heat exposure
Xiao Zhou1, Chanjuan Wei1, Zhuangzhuang Chen1
1Department of Neurology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Abstract:
Recent decades of epidemiological and clinical research have suggested that heat exposure could be a potential risk factor for ischemic stroke. Despite climate factors having a minor impact on individuals compared with established risk factors such as smoking, their widespread and persistent effects significantly affect public health. The mechanisms by which heat exposure triggers ischemic stroke are currently unclear. However, several potential mechanisms, such as the impact of temperature variability on stroke risk factors, inflammation, oxidative stress, and coagulation system changes, have been proposed. This article details the potential mechanisms by which heat exposure may induce ischemic stroke, aiming to guide the prevention and treatment of high-risk groups in hot climates and support public health policy development.
Related Concept Videos
Mechanisms of Heat Transfer
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant...
Mechanism of heat transfer
Mechanisms of Heat Transfer I
Mechanisms of Heat Transfer II
Homeostatic Imbalances in Body Temperature
Body Temperature

