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Confirmed Pathological Response to Nivolumab Combined with Chemotherapy for Advanced Gastric Cancer with Left
Naoto Morikawa1, Yuko Sato1,2, Noriyuki Iwama3
1Department of Medical Oncology, Tohoku Rosai Hospital.
Abstract:
We report the case of a 44-year-old male with advanced gastric cancer with distal lymph node metastasis who achieved a pathological complete response to chemotherapy combined with nivolumab. After five months of treatment, the patient underwent total gastrectomy with D2 lymph node dissection, and histological examination revealed the absence of malignant cells not only in the resected specimen but also in the harvested lymph nodes. At present, more than 1 year after the initial surgery, the patient is still alive without any recurrence. This case highlights the potential of chemotherapy combined with nivolumab to induce a complete response in advanced gastric cancer patients.
