Cardiac Angiosarcoma in the Right Atrium Treated by Surgical Resection

Area of Science:

• Cardiology
• Oncology
• Pathology

Background:

• Primary intracardiac angiosarcoma is a rare and aggressive malignancy.
• Early diagnosis and intervention are critical for patient outcomes.

Observation:

• A 49-year-old female presented with chest tightness, fatigue, and palpitations.
• Echocardiography revealed a right atrial mass, confirmed as high-grade angiosarcoma post-surgery.
• Recurrence with superimposed thrombus and Takotsubo cardiomyopathy were noted postoperatively.

Findings:

• Surgical excision and adjuvant chemotherapy with Paclitaxel were administered.
• Anticoagulation with Warfarin was initiated due to recurrent thrombus and cardiomyopathy.
• Cardiac MRI confirmed recurrent angiosarcoma with thrombus.

Implications:

• This case underscores the challenges in diagnosing and treating intracardiac angiosarcoma.
• Advanced imaging and meticulous postoperative surveillance are essential.
• Multidisciplinary management is key for optimizing care in complex cardiac tumor cases.