Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

316
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
316

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrospective analysis of open preperitoneal hernioplasty in emergency settings: clinical outcomes and challenges.

Hernia : the journal of hernias and abdominal wall surgery·2026
Same author

Multidisciplinary Treatment of Inguinoscrotal Sarcomas: Analysis of 39 Cases Treated by Surgical Approach.

Cancers·2026
Same author

Asparaginase Hypersensitivity Reactions in NK/T-Cell Lymphomas.

Clinics and practice·2025
Same author

Health-Related Quality of Life With Odronextamab Monotherapy for Relapsed/Refractory Follicular Lymphoma in the ELM-2 Study.

Clinical lymphoma, myeloma & leukemia·2025
Same author

"Cirugía Española": New time at the beginning of a new era.

Cirugia espanola·2025
Same author

Anti-CD19 CAR T-cell therapy for primary and secondary CNS lymphomas.

Bone marrow transplantation·2024

Related Experiment Video

Updated: Jun 14, 2025

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
04:40

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device

Published on: November 4, 2022

1.0K

Elective splenectomy for hematological diseases: a vanishing indication.

Sonia Fernández-Ananin1,2, Silvana Novelli3, Lorena Cambeiro Cabré4

  • 1Universitat Autònoma de Barcelona (UAB), Medical School, Upper Gastrointestinal and Bariatric Surgery Unit, Department of General and Digestive Surgery, Hospital de la Santa Creu i Sant Pau, Sant Quintí 89, 08041, Barcelona, Spain. Sonia.Fernandez@uab.cat.

Surgical Endoscopy
|August 29, 2024
PubMed
Summary

Splenectomy indications for hematological diseases, especially autoimmune conditions like immune thrombocytopenic purpura, have significantly decreased due to new therapies. Surgical teams must maintain skills for safe and efficient splenectomy when needed.

Keywords:
Autoimmune diseasesHematological diseasesImmune thrombocytopenic purpuraLaparoscopic splenectomyMedical therapies

More Related Videos

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

212
Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

160

Related Experiment Videos

Last Updated: Jun 14, 2025

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
04:40

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device

Published on: November 4, 2022

1.0K
Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

212
Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

160

Area of Science:

  • Hematology
  • Surgical Oncology
  • Immunology

Background:

  • Splenectomy has historically been a key treatment for hematological disorders.
  • Evolving medical therapies have altered traditional treatment guidelines for these conditions.
  • This study investigates the changing role of splenectomy in managing hematological diseases.

Purpose of the Study:

  • To evaluate the declining evidence for splenectomy in hematological indications.
  • To identify the reasons and justifications behind this shift in surgical practice.
  • To assess trends in splenectomy rates for various hematological conditions.

Main Methods:

  • A retrospective analysis of laparoscopic splenectomies for hematological diseases from 2010-2023.
  • Patients were categorized into autoimmune hemolytic diseases, lymphomas, myeloproliferative diseases, and other splenic conditions.
  • Data collected included annual splenectomy incidence, new case ratios, and surgical outcomes.

Main Results:

  • A significant progressive decrease in splenectomy indications was observed, particularly for autoimmune hemolytic diseases (p < 0.001).
  • Splenectomy for immune thrombocytopenic purpura dropped to zero, despite increased diagnoses (p < 0.001).
  • Indications for lymphoma remained consistent, while myeloproliferative disease-related splenectomies were rare.

Conclusions:

  • The study confirms a substantial decline in elective splenectomy for hematological diseases, primarily autoimmune conditions.
  • Awareness of this trend is crucial for surgical departments.
  • Maintaining surgical expertise in splenectomy is essential for patient safety and effective treatment when indicated.