Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Therapy00:59

Gene Therapy

25.3K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
25.3K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.7K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.7K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

21.9K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
21.9K
Adult Stem Cells01:33

Adult Stem Cells

28.0K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
28.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative outcomes of internal, external, and no stent in ureteroileal anastomosis for ileal orthotopic neobladder reconstruction.

Translational andrology and urology·2025
Same author

Proteomic analysis of oxidative stress response in human umbilical vein endothelial cells (HUVECs): role of heme oxygenase 1 (HMOX1) in hypoxanthine-induced oxidative stress in HUVECs.

Translational andrology and urology·2020
Same author

Total triterpenoids from Ganoderma Lucidum suppresses prostate cancer cell growth by inducing growth arrest and apoptosis.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban·2015
Same author

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase.

Oncotarget·2015
Same author

Antioxidative protective effect of icariin on the FeSO4/H 2O 2-damaged human sperm based on confocal raman micro-spectroscopy.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban·2014
Same author

Did prostate size affect the complication and outcome of plasmakinetic enucleation of the prostate?

International urology and nephrology·2014
Same journal

[Research progress on multimodal precision nursing interventions in urinary incontinence rehabilitation management after radical prostatectomy].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Dietary intervention to improve erectile dysfunction: Progress in research].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Tonifying kidney and activating blood therapy for the treatment of diabetic erectile dysfunction: A systematic review and meta-analysis].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Clinical effect of Huotujiji prescription on patients with asthenospermia of spleen-kidney yang-deficiency type].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Application of predictive nursing to the rehabilitation of patients after endoscopic surgery for prostate under the concept of enhanced recovery after surgery].

Zhonghua nan ke xue = National journal of andrology·2025
Same journal

[Influencing factors of lower urinary tract symptoms in patients after radical prostatectomy and nursing strategy].

Zhonghua nan ke xue = National journal of andrology·2025
See all related articles

Related Experiment Video

Updated: Jun 14, 2025

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.4K

[Progress in gene-modified stem cell therapy for penile erectile dysfunction].

Dao-Yuan Hu1,2, Heng-Jun Xiao1

  • 1Department of Urology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.

Zhonghua Nan Ke Xue = National Journal of Andrology
|August 29, 2024
PubMed
Summary
This summary is machine-generated.

Gene-modified stem cell therapy shows promise for treating erectile dysfunction (ED) by overcoming limitations of traditional stem cell therapy alone. This approach enhances stem cell performance for better ED treatment outcomes.

Keywords:
stem cell; erectile dysfunction; gene modification

More Related Videos

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
11:13

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

9.1K
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

595

Related Experiment Videos

Last Updated: Jun 14, 2025

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.4K
Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
11:13

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

9.1K
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

595

Area of Science:

  • Regenerative Medicine
  • Andrology
  • Cell Biology

Background:

  • Erectile dysfunction (ED) is a prevalent condition in men with limited effective treatments.
  • Stem cell (SC) therapy offers potential for ED treatment due to SC self-renewal and differentiation capabilities.
  • Limitations exist for SC therapy alone in treating complex ED.

Purpose of the Study:

  • To review recent advancements in gene-modified stem cell therapy for ED.
  • To explore how gene modification enhances SC performance for ED treatment.
  • To provide insights for future research in this area.

Main Methods:

  • Review of existing literature on gene-modified stem cell therapy for ED.
  • Analysis of studies focusing on enhanced SC functions through gene modification.
  • Synthesis of findings on the impact of gene-modified SC on ED pathology.

Main Results:

  • Gene modification can significantly improve SC efficacy in treating ED.
  • Targeted gene delivery enhances SC performance beyond conventional therapy.
  • Gene-modified SC therapy demonstrates potential for better outcomes in ED and related conditions.

Conclusions:

  • Gene-modified stem cell therapy is a promising and evolving area for ED treatment.
  • This approach offers a potential advantage over standard stem cell therapy for ED.
  • Further research is warranted to optimize gene-modified SC strategies for clinical application.