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Updated: May 7, 2026

Synthesis of an Intein-mediated Artificial Protein Hydrogel
Published on: January 27, 2014
Transient cucurbit[7]uril-mediated host-guest complexes for time-dependent fluorescence and information-self-erasing
Qian Wang1, Zhen Qi1, Hanren Xu1
1Key Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Researchers created a dynamic supramolecular system using cucurbituril. This system exhibits time-dependent fluorescence and assembly, enabling applications like fluorescent hydrogels for information encryption.
Area of Science:
- Supramolecular Chemistry
- Materials Science
- Biochemistry
Background:
- Non-equilibrium systems offer unique dynamic properties.
- Cucurbituril-based host-guest chemistry enables molecular recognition and assembly.
- Controlling pH over time is crucial for dynamic processes.
Purpose of the Study:
- To fabricate a non-equilibrium supramolecular host-guest system.
- To achieve time-dependent assembly and fluorescence.
- To develop a fluorescent hydrogel for information encryption.
Main Methods:
- Utilized urea/urease for pH control in aqueous solutions.
- Employed cucurbit[7]uril as the host molecule.
- Investigated dynamic assembly in hydrogel networks.
Main Results:
- Demonstrated transient assembly behavior.
- Observed time-dependent fluorescence.
- Successfully created a time-dependent fluorescent hydrogel.
Conclusions:
- A novel non-equilibrium cucurbituril-mediated supramolecular system was successfully fabricated.
- The system exhibits dynamic assembly and time-dependent fluorescence.
- The developed hydrogel holds potential for information encryption applications.
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