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Near Real-Time Syndromic Surveillance of Emergency Department Triage Texts Using Natural Language Processing: Case
Sedigh Khademi1,2, Christopher Palmer2, Muhammad Javed2
1Department of Paediatrics, University of Melbourne, Melbourne, Australia.
Insights
Transformer-based models significantly improve the detection of febrile convulsions in emergency departments using natural language processing. These advanced machine learning models enhance vaccine safety surveillance by analyzing triage notes for adverse events.
Area of Science:
- Medical informatics
- Public health surveillance
- Artificial intelligence in healthcare
Background:
- Adverse event detection post-immunization is crucial for public safety.
- Febrile convulsions are a known vaccine reaction in young children.
- Early identification of safety signals aids prompt intervention.
Purpose of the Study:
- To assess natural language processing (NLP) and machine learning (ML) for detecting febrile convulsions in emergency department (ED) triage notes.
- To determine optimal training data needs for ML models in this context.
- To evaluate real-time monitoring deployment requirements for ML models.
Main Methods:
- Developed a baseline pattern matching approach.
- Evaluated various ML models for febrile convulsion classification in ED triage notes.
- Compared model performance during training and on live ED data.
Main Results:
- Transformer-based models significantly outperformed standard neural networks.
- Transformer models demonstrated superior effectiveness in detecting febrile convulsions.
- The best models were resource-efficient and suitable for deployment.
Conclusions:
- NLP, especially large language models (LLMs), offers substantial benefits for syndromic surveillance.
- LLMs serve as highly effective classifiers for identifying adverse events.
- LLM text generation capabilities can improve training data quality and diversity.
Background:
Collecting information on adverse events following immunization from as many sources as possible is critical for promptly identifying potential safety concerns and taking appropriate actions. Febrile convulsions are recognized as an important potential reaction to vaccination in children aged <6 years.
Objective:
The primary aim of this study was to evaluate the performance of natural language processing techniques and machine learning (ML) models for the rapid detection of febrile convulsion presentations in emergency departments (EDs), especially with respect to the minimum training data requirements to obtain optimum model performance. In addition, we examined the deployment requirements for a ML model to perform real-time monitoring of ED triage notes.
Methods:
We developed a pattern matching approach as a baseline and evaluated ML models for the classification of febrile convulsions in ED triage notes to determine both their training requirements and their effectiveness in detecting febrile convulsions. We measured their performance during training and then compared the deployed models' result on new incoming ED data.
Results:
Although the best standard neural networks had acceptable performance and were low-resource models, transformer-based models outperformed them substantially, justifying their ongoing deployment.
Conclusions:
Using natural language processing, particularly with the use of large language models, offers significant advantages in syndromic surveillance. Large language models make highly effective classifiers, and their text generation capacity can be used to enhance the quality and diversity of training data.
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