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TUDCA inhibits EV71 replication by regulating ER stress signaling pathway and suppressing autophagy

Siwen Wang1, Rui Liu1, Yuting Zhou2

  • 1Molecular Diagnostic Laboratory, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210003, PR China; Children's Health Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210003, PR China; The Second Clinical College of Nanjing Medical University, Nanjing, Jiangsu 210011, PR China.

Diagnostic Microbiology and Infectious Disease
|August 30, 2024
PubMed

Keywords:
Activating transcription factor 6 (ATF6)AutophagyEndoplasmic reticulum stress (ER stress)Enterovirus 71 (EV71)Inositol-requiring enzyme 1 (IRE1)Protein kinase RNA-like ER kinase (PERK)Tauroursodeoxycholic acid (TUDCA)Unfolded protein response (UPR)

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