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Updated: May 5, 2026

08:54
Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
14.2K
[New oncological indications for liver transplantation]
Massimo Leo1,2, Lucia Zampaglione1, Nicolas Goossens1,2
1Service de gastroentérologie et hépatologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Revue Medicale Suisse
|September 2, 2024
Summary
Transplantation oncology, a specialized field of liver transplantation, shows excellent long-term outcomes for hepatocellular carcinoma. Emerging indications like cholangiocarcinoma and liver metastases also demonstrate superior results in select patients compared to systemic treatments.
Area of Science:
- Oncology
- Hepatobiliary Surgery
- Transplantation Medicine
Context:
- Liver transplantation is a complex procedure with evolving oncological applications.
- Hepatocellular carcinoma (HCC) is a well-established indication for liver transplantation.
- Emerging oncological indications are expanding the role of liver transplantation.
Purpose:
- To evaluate the efficacy of liver transplantation in managing primary and secondary liver cancers.
- To highlight the long-term outcomes of liver transplantation for hepatocellular carcinoma.
- To assess the potential of liver transplantation for other malignancies like cholangiocarcinoma, colorectal liver metastases, and neuroendocrine tumors.
Summary:
- Liver transplantation for hepatocellular carcinoma (HCC) yields excellent long-term results.
- Emerging indications including cholangiocarcinoma, hepatic metastases from colorectal cancer, and neuroendocrine tumors are being explored.
- In highly selected patients, liver transplantation offers superior outcomes compared to systemic treatments for these emerging indications.
Impact:
- Establishes liver transplantation as a viable and effective treatment modality for various liver malignancies.
- Provides a benchmark for comparing surgical outcomes with systemic therapies in advanced liver cancer.
- Suggests a paradigm shift in the management of complex liver cancers, prioritizing transplantation in select cases.
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