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Updated: Jun 14, 2025

Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
A Case of a Giant Siliconoma Mimicking Localized Breast Cancer
Virginie Van Boeckel1, Denis Danthine2, Jean-Luc Nizet1
1Department of Plastic, Reconstructive and Maxillofacial Surgery, University Hospital of Liège (CHU Liège), Liège, Belgium.
Abstract:
Silicone gel-filled breast implants are widely used for breast augmentation and reconstruction after mastectomy. However, there are some known complications associated with silicone implants: Leakage and migration of silicone particles from the implant cause a granulomatous reaction. Granulomas may present as masses with features of malignancy on breast MRI. We present a case of a giant breast siliconoma in a woman who had undergone reconstruction with breast prostheses, which were surgically removed because of rupture 8 years ago. Teaching point: Despite increasingly efficient diagnostic tools, siliconoma diagnosis remains challenging.

