Related Experiment Video

Updated: Jun 14, 2025

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

1.9K

A cavalpulmonary assist device utilising impedance pumping enhanced by peristaltic effect

Arthur P Burns-Cox1, Lian Gan1, Ashraf W Khir1

  • 1Department of Engineering, Durham University, Durham, UK.

The International Journal of Artificial Organs
|September 2, 2024
PubMed

Insights

A novel rotary pump shows promise for pediatric cavopulmonary support, addressing Fontan procedure complications. This pulsatile device is non-invasive to blood and suitable for children, warranting further development.

Area of Science:

  • Biomedical Engineering
  • Pediatric Cardiology
  • Medical Device Development

Background:

  • The Fontan procedure, a standard treatment for single ventricular defects, leads to long-term systemic complications due to inadequate pumping at the cavopulmonary junction.
  • Current ventricular assist devices (VADs) are often unsuitable for pediatric use, causing high shear rates in blood.

Purpose of the Study:

  • To demonstrate the feasibility of a novel, small, valveless, pulsatile rotary pump designed for cavopulmonary support.
  • The pump integrates impedance and peristaltic effects for non-invasive blood handling.

Main Methods:

  • A prototype pump was designed and fabricated in-house.
  • In vitro testing evaluated the effects of pumping frequency, pressure differences, and pump size on performance.

Main Results:

  • Net flow rate and pressure head delivery were linearly dependent on pumping frequency within physiological ranges.
  • The pump effectively regulated flow against favorable and adverse pressure gradients.
  • Performance was insensitive to device size.

Conclusions:

  • The feasibility of the novel rotary pump for pediatric cavopulmonary support is demonstrated under physiological conditions.
  • The device shows promise for future applications, with further investigation needed for miniaturization and hemolysis.
  • This innovative pump offers a potential solution for children with single ventricular defects.
Abstract

Keywords:
Paediatric VADimpedancenon-invasive to bloodperistalsispulsatilevalveless

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.5K
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

9.4K

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
118
Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
93
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
87
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
220
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
422