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Update on Takayasu arteritis: Year in review 2024
Prakashini Mruthyunjaya1, Ramnath Misra1
1Department of Clinical Immunology and Rheumatology, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, India.
Insights
This review summarizes recent advances in Takayasu arteritis, a rare large vessel vasculitis impacting young women. It covers new insights into clinical features, biomarkers, imaging, and treatments for this serious condition.
Area of Science:
- Rheumatology
- Internal Medicine
- Vascular Biology
Background:
- Takayasu arteritis is a rare systemic inflammatory large vessel vasculitis.
- It predominantly affects women in their third and fourth decades.
- Aortitis and its sequelae lead to significant morbidity and mortality.
Purpose of the Study:
- To review high-impact publications from 2023 to April 2024.
- To provide updates on clinical, biomarker, imaging, and pathogenetic aspects.
- To highlight recent therapeutic advancements in Takayasu arteritis management.
Main Methods:
- Systematic review of high-impact publications.
- Focus on literature published between 2023 and April 2024.
- Synthesis of information on clinical, diagnostic, and therapeutic progress.
Main Results:
- Recent publications offer new insights into Takayasu arteritis.
- Advances include novel biomarkers and improved imaging techniques.
- Updated therapeutic strategies show promise in patient management.
Conclusions:
- Continuous research is crucial for understanding and treating Takayasu arteritis.
- The review highlights significant progress in the field.
- Personalized treatment approaches remain key for managing this vasculitis.
Abstract:
Takayasu arteritis is an uncommon systemic inflammatory large vessel vasculitis affecting women in their third and fourth decades frequently. The disease poses considerable morbidity and mortality owing to the involvement of the aorta and its major branches. Treatment comprises medical and vascular interventions, tailored to each patient. We review the high-impact publications of the year 2023 up to April 2024, which provide great insight into clinical, biomarker, imaging, pathogenetic, and therapeutic updates.
