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Updated: Jun 14, 2025

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice
Published on: March 24, 2015
[Research Progress in Complement Receptor of the Immunoglobulin Superfamily in Regulating Liver Immunity]
Shu-Sen Yang1, Jing-Tao Li2, Shu-Guang Yan1
1Basic Medical College of Shaanxi University of Chinese Medicine,Xianyang,Shaanxi 712046,China.
Abstract:
Kupffer cells (KC),an important subset of immune cells in the liver,are essential for maintaining tissue homeostasis and responding quickly to liver damage.The complement receptor of the immunoglobulin superfamily (CRIg) is a receptor protein on the KC membrane.CRIg can not only capture pathogens in the blood flowing through the liver by complement binding but also mediate immune responses by regulating immune cells in the liver.Recent studies have confirmed the role of CRIg in regulating liver immunity.This article reviews the main modes of action of CRIg and the research progress of CRIg in regulating liver immunity.
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