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Newborn Filiform Periungual Hyperkeratosis: A Prospective Observational Study
Romina Cabrera1, Margarita Larralde1,2, Andrés Carvajal Jaimes1
1Pediatric Dermatology Department, Hospital General de Agudos "J. M. Ramos Mejía", Buenos Aires, Argentina.
Pediatric Dermatology
|September 3, 2024
Summary
Newborn filiform periungual hyperkeratosis (NFPH) affects nearly half of neonates, presenting as hard, nail fold elements. Early detection is crucial to prevent infections like acute paronychia.
Area of Science:
- Neonatal dermatology
- Dermatological conditions in newborns
Background:
- Newborn filiform periungual hyperkeratosis (NFPH) is a condition with unknown incidence and prevalence in neonates.
- Early diagnosis and treatment are vital to prevent complications such as acute paronychia.
Purpose of the Study:
- To describe the characteristics of NFPH in neonates.
- To determine the prevalence of NFPH in a neonatal population.
Main Methods:
- Prospective observational study.
- Inclusion of 100 neonates born in a referral hospital in Buenos Aires.
- Clinical examination for NFPH assessment.
Main Results:
- NFPH was found in 46% of the 100 neonates studied.
- The condition presented as hard, filiform elements, predominantly in bilateral lateral nail folds.
- Prevalence was higher on the right hand, with erosions noted due to easy detachment; two cases of secondary acute paronychia were treated successfully.
Conclusions:
- Clinical examination is important for screening NFPH in neonates.
- NFPH is a local factor predisposing neonatal patients to infection.
- Prompt identification and management can prevent complications.

