Related Experiment Video
Updated: Aug 15, 2026

Denver Papillae Protocol for Objective Analysis of Fungiform Papillae
Published on: June 8, 2015
Newborn Filiform Periungual Hyperkeratosis: A Prospective Observational Study
Romina Cabrera1, Margarita Larralde1,2, Andrés Carvajal Jaimes1
1Pediatric Dermatology Department, Hospital General de Agudos "J. M. Ramos Mejía", Buenos Aires, Argentina.
Introduction:
Newborn filiform periungual hyperkeratosis (NFPH) incidence and prevalence during the neonatal period remain unknown and have not been described in current literature. Timely diagnosis and treatment are essential to avoid complications during the neonatal period, such as acute paronychia.
Objective:
The aim of our prospective observational study was to describe the characteristics of NFPH in neonates born in a referral hospital in Buenos Aires.
Results:
One hundred patients were included. Most of them were male (60%). NFPH consists of hard, filiform elements, mostly present bilaterally in lateral nail folds. It was found in 46% of included patients. Prevalence was higher in the right hand. Due to a trend towards easy detachment and fracture, erosions were seen in several cases. Two cases of acute paronychia secondary to NFPH were diagnosed, with favorable outcomes after topical antibiotic treatment.
Conclusion:
The importance of clinical examination for screening of this local predisposing factor for infection in neonatal patients is highlighted.
More Related Videos
Related Concept Videos
Development of Human Microbiota
Development of the Oral Microbiota

