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Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Development of Immunocompetence01:22

Development of Immunocompetence

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

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Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Transcytosis of IgG01:15

Transcytosis of IgG

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Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
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A Murine Model of Group B Streptococcus Vaginal Colonization
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[Group A-streptococcal infection during pregnancy].

Ibtissam El Hasnaoui1, Jeffrey Hoek1, Eva Klijn2

  • 1Erasmus MC, Rotterdam. Afd. Verloskunde en Gynaecologie.

Nederlands Tijdschrift Voor Geneeskunde
|September 4, 2024
PubMed
Summary

Fulminant Group A-streptococcal (GAS) infection is a severe, rapidly progressing illness. This case report highlights a fatal instance of GAS toxic shock syndrome in a pregnant patient, emphasizing the need for prompt recognition and treatment.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Group A-streptococcal (GAS) infections can present with varying severity.

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  • Deep tissue GAS infections are associated with high morbidity and mortality.
  • Postpartum GAS infections are known for their potential severity.