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Giant metastatic mixed-type spinal ependymoma presenting with hydrocephalus
Anass Benomar1, Abdelhakim Khellaf2, Lynda Kadi1
1Department of Radiology, Radiation Oncology and Nuclear Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Quebec, Canada.
Retrograde dissemination of spinal ependymomas to the brain is rare. This case details a successful treatment for a 31-year-old female with hydrocephalus caused by spinal ependymoma metastasis.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Ependymomas are rare central nervous system tumors.
- Leptomeningeal dissemination is common, but retrograde spread from spine to brain is infrequent.
Observation:
- A 31-year-old female presented with hydrocephalus.
- She had an intracranial leptomeningeal metastasis from a giant spinal ependymoma with mixed histopathology.
Findings:
- The patient underwent surgical resection and whole-neuraxis radiotherapy.
- Successful treatment was achieved, highlighting an unusual pattern of tumor spread.
Implications:
- Ependymomas should be considered in atypical intracranial locations.
- Systematic neuraxis imaging is crucial for suspected ependymomas.
- Retrograde dissemination must be considered in cases with both intracranial and spinal lesions.
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