Related Experiment Video
Updated: Jun 14, 2025

06:37
Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
Published on: September 13, 2024
887
Therapeutic challenges in temporomandibular disorders
Smaranda Buduru1, Oana Almăşan1, Daniela Condor2
1Prosthetic Dentistry and Dental Materials Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Medicine and Pharmacy Reports
|September 5, 2024
Summary
Temporomandibular disorders (TMDs) often stem from muscle or joint issues, with iatrogenic causes prevalent. Treatment is complex, requiring multiple therapies, but most patients achieve symptom relief.
Area of Science:
- Dentistry
- Oral and Maxillofacial Surgery
- Pain Management
Background:
- Temporomandibular disorders (TMDs) encompass a range of conditions affecting the jaw joint and muscles.
- Etiology is multifactorial, including muscle impairment, joint issues, and iatrogenic factors.
Purpose of the Study:
- To evaluate the causes and treatment complexities of temporomandibular disorders (TMDs).
- To analyze treatment outcomes and challenges in a cohort of TMD patients.
Main Methods:
- A cohort of 160 subjects (76.3% female) diagnosed with TMDs was studied.
- A personalized coefficient assessed symptom resolution, secondary symptoms, patient collaboration, treatment duration, and cost.
Main Results:
- Muscle impairment (42.5%) and joint impairment (23.1%) were primary complaints.
- Iatrogenic etiology (69.4%) and untreated missing teeth (66.9%) were significant contributing factors.
- 82.3% of patients experienced primary symptom relief, with a 15.7% recurrence rate.
Conclusions:
- TMD treatment is complex, time-consuming, and demanding.
- Patients often require multiple therapies (4-7 types), increasing cost, duration, and patient discomfort.
Related Concept Videos
Tonsillitis II: Management
105
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
105
Teeth
361
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
361
Analgesia and Pain Management
552
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
552

