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Tranexamic Acid in Mohs Micrographic Surgery: A Systematic Review

Eenika A Kumar1, Lisa M Morris2, Basia M Michalski-McNeely2

  • 1University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|September 5, 2024
PubMed
Summary

Tranexamic acid (TXA) shows promise for hemostasis in Mohs surgery. This antifibrinolytic agent offers a safe and effective alternative to traditional methods, potentially improving patient outcomes and reducing bleeding.

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Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...