Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structural Joints: Fibrous Joints01:03

Structural Joints: Fibrous Joints

1.9K
Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
1.9K
Sutures of the Skull01:22

Sutures of the Skull

6.4K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.4K
Fibrous Proteins00:55

Fibrous Proteins

2.1K
Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
2.1K
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

3.1K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.1K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

5.7K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
5.7K
Fibril-associated Collagen01:11

Fibril-associated Collagen

2.5K
Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncertainty about others' trustworthiness increases during adolescence and guides social information sampling.

Scientific reports·2022
Same author

Radiological outcome after treatment of juvenile flatfeet with subtalar arthroereisis: a matched pair analysis of 38 cases comparing neurogenic and non-neurogenic patients.

Journal of children's orthopaedics·2019
Same author

[Slipped capital femoral epiphysis: clinical presentation, diagnostic procedure and classification].

Der Orthopade·2019
Same author

[Perthes disease-news in diagnostics and treatment].

Der Orthopade·2019
Same author

[Fixation techniques for slipped capital femoral epiphysis : Principles, surgical techniques, and complications].

Der Orthopade·2019
Same author

Poorer radiological outcome after delayed diagnosis and treatment in human position in Fettweis plaster cast in 93 unstable hip joints type D, III and IV according to Graf.

Journal of children's orthopaedics·2019
Same journal

[Lumbar disc herniation].

Orthopadie (Heidelberg, Germany)·2026
Same journal

[Surgical management of spinal metastases].

Orthopadie (Heidelberg, Germany)·2026
Same journal

[Minimally invasive surgery for insertional Achilles tendinopathy : Do Haglund resection, refixation of the Achilles tendon and Zadek osteotomy also work using minimally invasive techniques?]

Orthopadie (Heidelberg, Germany)·2026
Same journal

Orthopadie (Heidelberg, Germany)·2026
Same journal

[Extracorporeal magnetotransduction therapy in juvenile Perthes' disease : A case report].

Orthopadie (Heidelberg, Germany)·2026
Same journal

[Soft tissue engineering in orthopedics : Regenerative synergistic effects of shockwave therapy, PRP, EMTT, and hyaluronic acid].

Orthopadie (Heidelberg, Germany)·2026
See all related articles

Related Experiment Video

Updated: Jun 14, 2025

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
07:35

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

18.3K

[Fibrous dysplasia].

A Waltermann1, B Westhoff2

  • 1Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.

Orthopadie (Heidelberg, Germany)
|September 5, 2024
PubMed
Summary
This summary is machine-generated.

Fibrous dysplasia is a rare bone disorder where normal bone is replaced by fibrous tissue. Treatment focuses on managing symptoms like pain and fractures, as a cure is not possible.

Keywords:
Benign bone tumorBone deformitiesMcCune-Albright syndromePathological fractureSkeletal disease

More Related Videos

Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
07:48

Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice

Published on: September 16, 2019

9.8K
Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs
08:40

Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs

Published on: April 19, 2024

2.0K

Related Experiment Videos

Last Updated: Jun 14, 2025

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
07:35

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

18.3K
Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
07:48

Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice

Published on: September 16, 2019

9.8K
Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs
08:40

Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs

Published on: April 19, 2024

2.0K

Area of Science:

  • Orthopedics
  • Pathology
  • Radiology

Context:

  • Fibrous dysplasia is a benign skeletal disease.
  • It involves the replacement of normal bone with fibrous tissue.
  • Manifestations range from asymptomatic to severe disability.

Purpose:

  • To describe the characteristics of fibrous dysplasia.
  • To outline diagnostic methods.
  • To detail current treatment strategies.

Summary:

  • Fibrous dysplasia presents as monostotic or polyostotic forms.
  • Radiological diagnosis shows a characteristic "cloudy, frosted glass" appearance.
  • Management includes pain relief, stabilization, deformity correction, and antiresorptive medication.

Impact:

  • Provides a comprehensive overview of fibrous dysplasia.
  • Highlights the importance of orthopedic interventions.
  • Informs clinical management and patient care.