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Differentiated Thyroid Cancer after Thyroidectomy.

Wei Ming Chua1, Charlene Yu Lin Tang1, Kelvin S H Loke1

  • 1From the Department of Nuclear Medicine and Molecular Imaging, Division of Radiological Sciences, Singapore General Hospital, Outram Rd, Singapore 169608 (W.M.C., C.Y.L.T., K.S.H.L., W.W.C.L.); Department of Neuroradiology, Singapore General Hospital, Singapore (W.M.C., M.S.L., W.H., M.Y.S.L., K.C.L., R.C.C.); Radiological Sciences Academic Clinical Program, SingHealth Duke-NUS Academic Medical Centre, Singapore (W.M.C., C.Y.L.T., K.S.H.L., W.W.C.L., M.S.L., W.H., M.Y.S.L., K.C.L., R.C.C.); National Neuroscience Institute, Singapore (W.M.C., M.S.L., W.H., M.Y.S.L., K.C.L., R.C.C.); Department of Medicine, Division of Endocrinology, National University Hospital, Singapore (S.P.Y.); and Yong Loo Lin School of Medicine, National University of Singapore, Singapore (S.P.Y.).

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|September 5, 2024
PubMed
Summary
This summary is machine-generated.

Increased detection of differentiated thyroid cancer (DTC) is common. Radiologists are key in detecting recurrent DTC after surgery using imaging, guiding patient treatment and surveillance.

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Area of Science:

  • Radiology and Imaging
  • Oncology
  • Endocrinology

Background:

  • Widespread use of neck ultrasonography (US) and other imaging leads to increased detection of differentiated thyroid cancer (DTC).
  • While many DTCs are indolent, a subset of patients require surgery and may experience recurrence, commonly in lymph nodes or distant sites.
  • Radiologists are crucial in postoperative surveillance for detecting recurrent DTC and guiding treatment.

Purpose of the Study:

  • To provide a comprehensive overview of the postoperative evaluation of differentiated thyroid cancer (DTC).
  • To highlight the role of radiologists in detecting recurrent DTC using various imaging modalities.
  • To emphasize the importance of correlating imaging findings with clinical status and biochemical markers.

Main Methods:

  • Review of imaging modalities used in postoperative evaluation of DTC, including ultrasonography (US), CT, MRI, radioactive iodine imaging, and PET/CT.
  • Discussion of the imaging characteristics of recurrent DTC.
  • Emphasis on integrating clinical and biochemical data with imaging interpretation.

Main Results:

  • Ultrasonography (US) is the primary imaging modality for postoperative evaluation of DTC.
  • Multimodality imaging (CT, MRI, radioactive iodine imaging, PET/CT) aids in accurate diagnosis and characterization of recurrent disease.
  • Correlation of imaging findings with clinical status and biochemical markers is essential for accurate interpretation and minimizing errors.

Conclusions:

  • Radiologists require a thorough understanding of imaging techniques and recurrent DTC characteristics for effective postoperative surveillance.
  • Multimodality imaging plays a vital role in the diagnosis and management of recurrent DTC.
  • Integrated interpretation of imaging, clinical, and biochemical data optimizes patient care for recurrent DTC.