Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique

The challenge of drug discovery of a GPCR target: analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists.

Biochemical pharmacology·2006

Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.

Neuropharmacology·2005

Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity.

Neuropharmacology·2003

Species-related pharmacological heterogeneity of histamine H(3) receptors.

European journal of pharmacology·2002

Comparison of alpha 1-adrenoceptor agonists in canine urethral pressure profilometry and abdominal leak point pressure models.

The Journal of urology·2001

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

Molecular pharmacology·2026

Anchored kinase and phosphatase signaling networks in amyloid β-induced synaptic dysfunction.

Molecular pharmacology·2026

Where are peptide ligands of potassium channels sourced from?

Molecular pharmacology·2026

Regulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6.

Molecular pharmacology·2026

Neuroprotective in vitro effects of histone deacetylase 6-selective inhibitor SW-100 toward oxaliplatin-derived toxicity.

Molecular pharmacology·2026

Emerging roles of platelet DNA in cancer detection and noninvasive prenatal testing.

Molecular pharmacology·2026

Reconstitution of lamin assembly on nuclear pore complex-containing membranes.

Journal of cell science·2026

Biomimetic stress granules replenish lysosomal repair to reinstate macrophage immunometabolic antibacterial programs.

Bioactive materials·2026

Theoretical Analysis of Androstenone Adsorption on Chimpanzee and Gorilla Olfactory Receptors (G-Protein): Statistical Physics Modeling, Molecular Docking Simulation, and Thermodynamic Investigation.

Proteins·2026

Beyond cultured cells: Frontiers in in situ structural biology.

Current opinion in structural biology·2026

Filtering Disordered Protein Conformations by NMR Residual Dipolar Couplings.

The journal of physical chemistry. B·2026

Capturing molecular handshakes: PhIX-MS reveals transient interactions that control the proteasome complex.

Molecular cell·2026

Related Experiment Videos

Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a

Related Concept Videos

The challenge of drug discovery of a GPCR target: analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists.

Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.

Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity.

Species-related pharmacological heterogeneity of histamine H(3) receptors.

Comparison of alpha 1-adrenoceptor agonists in canine urethral pressure profilometry and abdominal leak point pressure models.

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

Anchored kinase and phosphatase signaling networks in amyloid β-induced synaptic dysfunction.

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Regulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6.

Neuroprotective in vitro effects of histone deacetylase 6-selective inhibitor SW-100 toward oxaliplatin-derived toxicity.

Emerging roles of platelet DNA in cancer detection and noninvasive prenatal testing.

Reconstitution of lamin assembly on nuclear pore complex-containing membranes.

Biomimetic stress granules replenish lysosomal repair to reinstate macrophage immunometabolic antibacterial programs.

Theoretical Analysis of Androstenone Adsorption on Chimpanzee and Gorilla Olfactory Receptors (G-Protein): Statistical Physics Modeling, Molecular Docking Simulation, and Thermodynamic Investigation.

Beyond cultured cells: Frontiers in in situ structural biology.

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Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a