A silent strain: the unseen burden of acute respiratory infections in children

Riccardo Boracchini1, Benedetta Canova2, Pietro Ferrara3

  • 1Department of Statistics and Quantitative Methods, Division of Biostatistics, Epidemiology and Public Health, Laboratory of Healthcare Research and Pharmacoepidemiology, University of Milan-Bicocca, Via Bicocca Degli Arcimboldi, 8, Milan, 20126, Italy. riccardo.boracchini@unimib.it.

PubMed

Insights

This study analyzed over 1.4 million pediatric acute respiratory infections (ARIs) in Italy. Lower respiratory tract infections place a higher burden on healthcare, highlighting the need for targeted management in child health.

Area of Science:

  • Pediatric infectious diseases
  • Public health surveillance
  • Healthcare system burden analysis

Background:

  • Acute respiratory tract infections (ARIs) significantly impact healthcare systems through emergency admissions and medication use.
  • Understanding the burden of ARIs in pediatric community care is crucial for developing effective public health interventions.
  • Real-world data from an Italian pediatric network (Pedianet) was utilized to assess ARI-related healthcare utilization.

Discussion:

  • The study quantified ARI burden using follow-up visits per 100 cases, stratified by infection type and season.
  • Lower respiratory tract infections (LRIs) demonstrated a substantially higher healthcare burden compared to upper respiratory tract infections (URIs).
  • Pneumonia incidence showed a pre-pandemic decline followed by a post-COVID-19 rebound, indicating evolving epidemiological trends.

Key Insights:

  • A total of 1,402,953 ARI visits were analyzed, with an overall rate of 12 visits per 100 cases.
  • LRIs accounted for 29 follow-up visits per 100 cases, significantly exceeding the 9 visits per 100 cases for URIs.
  • Pneumonia trends shifted post-COVID-19, emphasizing the dynamic nature of pediatric respiratory infections.

Outlook:

  • Continuous monitoring of pediatric ARIs is essential for public health planning.
  • Targeted interventions for LRIs are recommended to alleviate healthcare system strain.
  • Further research into post-pandemic trends of pediatric respiratory infections is warranted.

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